Medicated effect of CDKN1B on promoting proliferation of islet β cells in diabetes mellitus / 中国综合临床
Clinical Medicine of China
;
(12): 233-236, 2023.
Artículo
en Chino
| WPRIM
| ID: wpr-992495
ABSTRACT
The serious decrease in the number of functional β cells is one of the main features in the pathogenesis of diabetes mellitus. CDKN1B is a new kind of regulatory protein, which can bind and inactivate cyclin and cyclin-dependent kinase complex to control the process of cell cycle. It was suggested that down-regulation or deletion of CDKN1B in islet β cells could accelerate the proliferation of islet β cells, thus increasing the number of islet β cells, which is of great significance for treatments of diabetes.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Clinical Medicine of China
Año:
2023
Tipo del documento:
Artículo
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