The role and treatment strategy of epithelial-mesenchymal transition in radiation-induced pulmonary fibrosis / 中华放射医学与防护杂志
Chinese Journal of Radiological Medicine and Protection
;
(12): 307-313, 2023.
Artículo
en Chino
| WPRIM
| ID: wpr-993090
ABSTRACT
Radiation-induced pulmonary fibrosis (RIPF) is one of the most serious late complications after nuclear radiation accident, bone marrow transplantation pretreatment and thoracic tumor radiotherapy. The formation process of RIPF is complicated and the pathogenesis has not been fully elucidated. Recent studies have shown that radiation-induced epithelial-mesenchymal transition (EMT) of lung epithelial cells is an indispensable segment of RIPF. This article reviews the role of radiation-induced lung EMT in the occurrence and development of RIPF and related drugs with EMT as a potential therapeutic target, providing ideas for the development of therapeutic drugs for RIPF in the future.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Chinese Journal of Radiological Medicine and Protection
Año:
2023
Tipo del documento:
Artículo
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