Early thrombotic risks and prophylactic anticoagulation after liver transplantation / 中华器官移植杂志
Chinese Journal of Organ Transplantation
; (12): 53-61, 2023.
Article
en Zh
| WPRIM
| ID: wpr-994632
Biblioteca responsable:
WPRO
ABSTRACT
In early stage after liver transplantation(LT), coagulation function of recipients stays in a fragile balance. Affected by a variety of complex mechanisms, blood is usually hypercoagulable. An imbalance between coagulation factors and physiological anticoagulants, elevated level of vWF, an occurrence of fibrinolysis inhibition and dosing of immunosuppressive agents cause a hypercoagulable state in an early stage after LT. Blood hypercoagulability may lead to such thrombotic complications as hepatic artery, portal vein and deep vein thromboses. Some studies have demonstrated that postoperative prophylactic anticoagulation has some effect in reducing the risks of early postoperative thrombosis. However, there is still a great lack of high-quality evidence. This review summarized the latest researches on early coagulation dysfunction, thrombosis and preventive anticoagulation after LT.
Texto completo:
1
Índice:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Organ Transplantation
Año:
2023
Tipo del documento:
Article