Research progress in neutrophil extracellular traps in obstetrics / 中华围产医学杂志

ABSTRACT

Neutrophils plays an essential role in innate immunity. Neutrophil extracellular traps (NETs) are released by activated neutrophils in response to infection. However, excessive NETs can result in body dysfunction and organ damage and participate in several pathological conditions. This paper mainly focuses on the formation, regulatory mechanism and role of NETs in obstetric diseases, such as preeclampsia, gestational diabetes mellitus and preterm birth, and listed the current medications used to block the formation of NETs in obstetrics.