Common problems and considerations in challenge tests of different animal models of SARS-CoV-2 vaccine / 中国生物制品学杂志
Chinese Journal of Biologicals
; (12): 1149-1152, 2023.
Article
en Zh
| WPRIM
| ID: wpr-996609
Biblioteca responsable:
WPRO
ABSTRACT
@#Animal challenge test is an effective means to study the efficacy of severe acute respiratory symptom coronavirus 2(SARS-CoV-2)vaccine. The appropriate animal models and reasonable experimental design play an important role in obtaining efficacy and safety information,as well as supporting clinical trials. At present,common non-clinical animal models include transgenic mice,non-human primates,hamsters,ferrets and so on. This paper reviews the common animal models used in non-clinical trials and the problems encountered in their application.
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Índice:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Biologicals
Año:
2023
Tipo del documento:
Article