Cutaneous collagenous vasculopathy: light and transmission electron microscopy
An. bras. dermatol
;
94(2): 211-213, Mar.-Apr. 2019. graf
Article
Dans Anglais
| LILACS
| ID: biblio-1001126
ABSTRACT
Abstract Cutaneous collagenous vasculopathy is a rare acquired idiopathic microangiopathy characterized by progressive development of diffuse asymptomatic telangiectasias and histologically by accumulation of collagen type IV around the affected vessels. It is diagnosed by its clinical history, confirmed by light microscopy with collagen-specific immunostaining. We report a case of a patient with extensive acquired telangiectasias on the left arm, clinically resembling unilateral nevoid telangiectasia. Dilated blood vessels with thickened walls were observed in the dermis. Immunohistochemistry with collagen IV antibodies revealed marked collagen deposition around the vessels, confirming the diagnosis. Transmission electron microscopy observed duplicate and triplicate vascular basal membrane associated with deposition of amorphous material around the membranes.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Télangiectasie
/
Dermatoses vasculaires
/
Maladies du collagène
Limites du sujet:
Femelle
/
Humains
langue:
Anglais
Texte intégral:
An. bras. dermatol
Thème du journal:
Dermatologie
Année:
2019
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Dermacenter Alto Vale/BR
/
Fundação Universidade de Rio Grande/BR
/
Universidade Católica de Pelotas/BR
/
Universidade Federal de Pelotas/BR
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