Telomere length and childhood trauma in Colombians with depressive symptoms
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
;
41(3): 194-198, May-June 2019. tab
Article
Dans Anglais
| LILACS
| ID: biblio-1011493
ABSTRACT
Objective:
Childhood trauma and telomere length (TL) are important risk factors for major depressive disorder. We examined whether there was an association between childhood trauma and TL in a sample of Colombians who were assessed for depressive symptoms.Methods:
We applied the Center for Epidemiologic Studies Depression scale, the Patient Health Questionnaire-9, the Hospital Anxiety and Depression scale and the Childhood Trauma Questionnaire to 92 Colombian subjects (mean age = 21). TL was measured with quantitative PCR. Spearman's correlation coefficient (rs) was used to analyze the relationship between childhood trauma scores and TL.Results:
We found a significant correlation between TL and sexual abuse scores (rs = 0.428, p = 0.002) in individuals with higher depressive symptom scores.Conclusion:
This is the first report of a significant association between TL and sexual abuse in a Latin American sample and provides additional evidence about the role of childhood trauma and TL in neuropsychiatric disorders.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Maltraitance des enfants
/
Télomère
/
Trouble dépressif majeur
/
Raccourcissement des télomères
Type d'étude:
Etude diagnostique
/
Recherche qualitative
/
Facteurs de risque
Limites du sujet:
Enfant
/
Femelle
/
Humains
/
Mâle
Pays comme sujet:
Amérique du Sud
/
Colombie
langue:
Anglais
Texte intégral:
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
Thème du journal:
Psychiatrie
Année:
2019
Type:
Article
Pays d'affiliation:
Colombie
/
Espagne
Institution/Pays d'affiliation:
Universidad Antonio Nariño/CO
/
University of Barcelona/ES
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS