Comparative study of four different types of intraperitoneal mesh prostheses in rats
Acta cir. bras
;
34(7): e201900703, 2019. tab, graf
Article
Dans Anglais
| LILACS
| ID: biblio-1038114
ABSTRACT
Abstract Purpose:
To compare four types of mesh regarding visceral adhesions, inflammatory response and incorporation.Methods:
Sixty Wistar rats were divided into four groups, with different meshes implanted intraperitoneally polytetrafluoroethylene (ePTFE group); polypropylene with polydioxanone and oxidized cellulose (PCD); polypropylene (PM) and polypropylene with silicone (PMS). The variables analyzed were area covered by adhesions, incorporation of the mesh and inflammatory reaction (evaluated histologically and by COX2 immunochemistry).Results:
The PMS group had the lowest adhesion area (63.1%) and grade 1 adhesions. The ePTFE and PM groups presented almost the total area of their surface covered by adherences (99.8% and 97.7% respectively) The group ePTFE had the highest percentage of area without incorporation (42%; p <0.001) with no difference between the other meshes. The PMS group had the best incorporation rate. And the histological analysis revealed that the inflammation scores were significantly different.Conclusions:
The PM mesh had higher density of adherences, larger area of adherences, adherences to organs and percentage of incorporation. ePTFE had the higher area of adherences and lower incorporation. The PMS mesh performed best in the inflammation score, had a higher incorporation and lower area of adherences, and it was considered the best type of mesh.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Prothèses et implants
/
Filet chirurgical
/
Adhérences tissulaires
/
Hernie incisionnelle
/
Inflammation
Limites du sujet:
Animaux
langue:
Anglais
Texte intégral:
Acta cir. bras
Thème du journal:
Chirurgie générale
/
Procedimentos Cir£rgicos Operat¢rios
Année:
2019
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
UNIFESP/BR
/
Universidade Federal de São Paulo/BR
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