Local dermal application of a compound lidocaine cream in pain management of cancer wounds
Braz. j. med. biol. res
;
52(11): e8567, 2019. tab, graf
Article
Dans Anglais
| LILACS
| ID: biblio-1039265
ABSTRACT
The aim of this study was to explore the analgesic effect of local application of compound lidocaine/prilocaine cream on cancer wounds during wound care in order to reduce the amount of morphine intake or completely replace the systemic morphine administration and optimize the protocol for cancer wound pain management. All patients were enrolled with a visual analog scale (VAS) pain score ≥4. Before wound care, 60 patients were randomly divided into 2 groups of 30 each morphine group (10 mg tablet); topical 5% compound lidocaine cream group (0.2 g/cm2). VAS scores, heart rate, and Kolcaba comfort level were recorded for the two groups 10 min before and 10, 15, 20, and 25 min after wound care and data were analyzed statistically. The means for the pain score and heart rate of the topical lidocaine/prilocaine cream group were lower than those of the morphine group (P<0.01) and the Kolcaba comfort level was higher (P<0.01). Local dermal application of the compound lidocaine cream can be used as an alternative to the systemic morphine administration in cancer wound care for its safety and effectiveness. In addition, it can improve the patients' comfort and quality of life.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Plaies et blessures
/
Anesthésiques combinés
/
Gestion de la douleur
/
Association de lidocaïne et de prilocaïne
/
Tumeurs
Type d'étude:
Essai clinique contrôlé
/
Etude d'étiologie
Limites du sujet:
Adulte
/
Adulte très âgé
/
Femelle
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Braz. j. med. biol. res
Thème du journal:
Biologie
/
Médicament
Année:
2019
Type:
Article
Pays d'affiliation:
Chine
Institution/Pays d'affiliation:
Huazhong University of Science and Technology/CN
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