Emergence of Trichosporon mycotoxinivorans (Apiotrichum mycotoxinivorans) invasive infections in Latin America
Mem. Inst. Oswaldo Cruz
;
112(10): 719-722, Oct. 2017. graf
Article
Dans Anglais
| LILACS
| ID: biblio-1040562
ABSTRACT
We report the first two cases of Trichosporon mycotoxinivorans infections in Latin America. We also conducted a literature review and a microbiological investigation, including that of clinical and environmental isolates. A 30-year-old man with chronic renal failure had disseminated infection after dialysis and a 15-year-old boy with cystic fibrosis (CF) had pulmonary exacerbations with positive respiratory samples. A review of the relevant literature revealed that deep-seated infections were related to immunosuppression or invasive devices, while most of the CF patients showed a decline in lung function after positive cultures. Phylogenetic analyses revealed three distinct circulating genotypes. MALDI-TOF mass spectrometry analysis showed similar spectral profiles and correctly identified all strains/isolates. Biofilm production was documented in a bloodstream isolate and biofilm-producing cells showed high minimum inhibitory concentrations against antifungals.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Trichosporon
/
Trichosporonose
Type d'étude:
Étude pronostique
Limites du sujet:
Adolescent
/
Adulte
/
Humains
/
Mâle
Pays comme sujet:
Amérique du Sud
/
Brésil
langue:
Anglais
Texte intégral:
Mem. Inst. Oswaldo Cruz
Thème du journal:
Médecine tropicale
/
Parasitologie
Année:
2017
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Universidade Federal da Bahia/BR
/
Universidade Federal de Alfenas/BR
/
Universidade Federal de São Paulo/BR
/
Universidade de São Paulo/BR
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