Poor sensitivity of rapid tests for the detection of antibodies to the hepatitis B virus: implications for field studies
Mem. Inst. Oswaldo Cruz
;
112(3): 209-213, Mar. 2017. tab
Article
Dans Anglais
| LILACS
| ID: biblio-1040567
ABSTRACT
Rapid tests (RTs) can be used as an alternative method for the conventional diagnosis of hepatitis B virus (HBV). This study aims to evaluate antibodies to HBsAg (anti-HBs) and antibodies to HBeAg (anti-HBe) RTs under different Brazilian settings. The following three groups were included GI viral hepatitis outpatient services; GII low resource areas; and GIII crack users and beauticians. Imuno-rápido anti-HBsAg™ and Imuno-rápido anti-HBeAg™ RTs were evaluated and showed specificities greater than 95% in all groups. The sensitivity values to anti-HBs were 50.38%, 51.05% and 46.73% and the sensitivity values to anti-HBe were 76.99%, 10.34% and 11.76% in the GI, GII and GIII groups, respectively. The assays had a low sensitivity and high specificity, which indicated their use for screening in regions endemic for HBV.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Virus de l'hépatite B
/
Hépatite B
/
Anticorps de l'hépatite B
/
Antigènes e du virus de l'hépatite virale B
/
Antigènes de surface du virus de l'hépatite B
Type d'étude:
Etude diagnostique
Limites du sujet:
Adulte
/
Humains
langue:
Anglais
Texte intégral:
Mem. Inst. Oswaldo Cruz
Thème du journal:
Médecine tropicale
/
Parasitologie
Année:
2017
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Fundação Oswaldo Cruz-Fiocruz/BR
/
Hospital São Lucas/BR
/
Universidade Federal do Mato Grosso do Sul/BR
/
Universidade Federal do Rio de Janeiro/BR
/
Universidade Federal do Tocantins/BR
/
Universidade de Brasília/BR
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