The use of circulating cathodic antigen rapid test and serology for diagnosis of active Schistosoma mansoni infection in migrants in Italy, a non-endemic country: a cross sectional study
Mem. Inst. Oswaldo Cruz
;
112(6): 452-455, June 2017. tab
Article
Dans Anglais
| LILACS
| ID: biblio-1040569
ABSTRACT
ABSTRACT Diagnosis of schistosomiasis in migrants coming from endemic areas can be difficult, especially in asymptomatic subjects. Light-intensity disease, in fact, may be missed due to the low sensitivity of the stool microscopy and serologic testing cannot distinguish between a resolved infection and an active infection in patients who have been infected and treated in the past, because specific antibodies can persist despite cure. We describe a cross-sectional study conducted on 82 migrants tested for Schistosoma mansoni on single blood (anti-schistosome antibodies, total IgE) and urine [point-of-care (POC) circulating-cathodic-antigen (CCA) test] samples. A positive POC-CCA test (active infection) resulted in two untreated patients with a positive serology while all patients (n = 66) with a past infection showed a negative POC-CCA test. POC-CCA urine test in combination with serology may be helpful in rapidly differentiate active from past S. mansoni infection in migrants coming from endemic areas.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Schistosoma mansoni
/
Population de passage et migrants
/
Schistosomiase à Schistosoma mansoni
/
Antigènes d'helminthe
Type d'étude:
Etude diagnostique
/
Étude observationnelle
/
Étude de prévalence
/
Facteurs de risque
Limites du sujet:
Animaux
/
Femelle
/
Humains
/
Mâle
Pays comme sujet:
Europe
langue:
Anglais
Texte intégral:
Mem. Inst. Oswaldo Cruz
Thème du journal:
Médecine tropicale
/
Parasitologie
Année:
2017
Type:
Article
Pays d'affiliation:
République centrafricaine
/
Italie
Institution/Pays d'affiliation:
San Raffaele Scientific Institute/IT
/
Society of Priests of the Sacred Heart of Betharram/CF
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