Preliminary assessment of anti-α-Gal IgG and IgM levels in patients with patent Plasmodium vivax infection
Mem. Inst. Oswaldo Cruz
;
114: e190145, 2019. tab, graf
Article
Dans Anglais
| LILACS
| ID: biblio-1040609
ABSTRACT
Anti-α-Gal responses may exert a protective effect in falciparum malaria. However, the biological role of such antibodies is still unknown during Plasmodium vivax infections. We investigated IgG and IgM responses to α-Gal in individuals with vivax malaria. Anti-α-Gal IgG and IgM levels were higher in these patients than in controls, but no significant correlation was found between parasitaemia and anti-α-Gal response, nor between this response and ABO blood group status. This is the first study to investigate anti-α-Gal antibodies in P. vivax-infected patients; a larger survey is necessary to achieve a better understanding of host immune response during vivax malaria.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Plasmodium vivax
/
Immunoglobuline G
/
Immunoglobuline M
/
Anticorps anti-idiotypiques
/
Paludisme à Plasmodium vivax
Limites du sujet:
Adulte
/
Humains
langue:
Anglais
Texte intégral:
Mem. Inst. Oswaldo Cruz
Thème du journal:
Médecine tropicale
/
Parasitologie
Année:
2019
Type:
Article
Pays d'affiliation:
Brésil
/
États-Unis d'Amérique
Institution/Pays d'affiliation:
Georgia Institute of Technology/US
/
Universidade Federal de Minas Gerais/BR
/
Universidade Federal do Mato Grosso/BR
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