Sporothrix brasiliensis produces the highest levels of oxidative stress in a murine model among the species of the Sporothrix schenckii complex
Rev. Soc. Bras. Med. Trop
;
50(4): 554-557, July-Aug. 2017. graf
Article
Dans Anglais
| LILACS
| ID: biblio-1041421
ABSTRACT
Abstract INTRODUCTION:
We compared indicators of oxidative stress in the tissue of mice infected with strains from Sporothrix schenckii complex.METHODS:
Mice were inoculated with Sporothrix brasiliensis, Sporothrix schenckii sensu stricto, Sporothrix globosa, Sporothrix mexicana or Sporothrix albicans. The activity of catalase and glutathione were accessed in the liver and spleen.RESULTS:
Animals infected with S. brasiliensis exhibited splenomegaly and significant decrease in catalase activity, and protein and non-protein thiol content compared to animals infected with the other species.CONCLUSIONS:
Sporothrix brasiliensis exhibits higher pathogenicity compared to other species of the Sporothrix schenckii complex by increasing oxidative stress in animal tissue.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Rate
/
Sporotrichose
/
Stress oxydatif
/
Foie
Limites du sujet:
Animaux
/
Humains
Pays comme sujet:
Amérique du Sud
/
Brésil
langue:
Anglais
Texte intégral:
Rev. Soc. Bras. Med. Trop
Thème du journal:
Médecine tropicale
Année:
2017
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Imed/BR
/
Universidade Federal de Santa Maria/BR
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