Negative serology of Fasciola hepatica infection in patients with liver cancer in Peru: a preliminary report
Rev. Soc. Bras. Med. Trop
;
51(2): 231-233, Mar.-Apr. 2018. tab
Article
Dans Anglais
| LILACS
| ID: biblio-1041452
ABSTRACT
Abstract INTRODUCTION:
The etiology of several hepatocellular carcinoma (HCC) cases remains largely unknown. Although Fasciola hepatica has been associated with liver fibrosis in Latin America, it has not yet been associated with HCC. This study aimed to determine the existence of specific IgG antibodies against F. hepatica in the serum samples of HCC patients. METHODS In total, 13 serum samples from 13 HCC patients were screened using Fas2-ELISA. RESULTS Fas2-ELISA demonstrated negative results in all HCC patients included in this study. CONCLUSIONS The pre-existence of F. hepatica infection in HCC patients needs to be further investigated in epidemiological and experimental studies.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Immunoglobuline G
/
Anticorps antihelminthe
/
Carcinome hépatocellulaire
/
Fasciola hepatica
/
Fasciolase
/
Tumeurs du foie
Type d'étude:
Etude diagnostique
/
Etude d'étiologie
Limites du sujet:
Aged80
/
Animaux
/
Femelle
/
Humains
/
Mâle
Pays comme sujet:
Amérique du Sud
/
Pérou
langue:
Anglais
Texte intégral:
Rev. Soc. Bras. Med. Trop
Thème du journal:
Médecine tropicale
Année:
2018
Type:
Article
Pays d'affiliation:
France
/
Pérou
/
États-Unis d'Amérique
Institution/Pays d'affiliation:
Instituto Nacional de Enfermedades Neoplásicas/PE
/
Stony Brook University/US
/
Universidad Peruana Cayetano Heredia/PE
/
Université de Toulouse/FR
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