Clinico-immunological spectrum of American tegumentary leishmaniasis and leprosy coinfection: A case series in Southeastern Brazil
Rev. Soc. Bras. Med. Trop
;
52: e20180172, 2019. tab, graf
Article
Dans Anglais
| LILACS
| ID: biblio-1041541
ABSTRACT
Abstract INTRODUCTION:
American tegumentary leishmaniasis (ATL) and leprosy share common areas of prevalence, but reports of coinfection are scarce.METHODS:
We report a series of 9 ATL-leprosy cases and discuss the association. An integrative diagram to analyze the clinico-immunological features of coinfection with both diseases.RESULTS:
Nine patients with leishmaniasis (5 cutaneous, 3 mucocutaneous, 1 disseminated case) exhibited concurrent infection with distinct clinical forms of leprosy. Our diagram-based analysis evidenced a divergent clinico-immunological spectrum for each disease in 8 out of 9 cases.CONCLUSIONS:
The spectrum of ATL-leprosy comorbidity suggests that the host has a specific immune response against each pathogen.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Leishmaniose cutanée
/
Lymphocytes auxiliaires Th2
/
Lymphocytes auxiliaires Th1
/
Lèpre
Type d'étude:
Facteurs de risque
Limites du sujet:
Adulte très âgé
/
Aged80
/
Femelle
/
Humains
/
Mâle
Pays comme sujet:
Amérique du Sud
/
Brésil
langue:
Anglais
Texte intégral:
Rev. Soc. Bras. Med. Trop
Thème du journal:
Médecine tropicale
Année:
2019
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Universidade de Brasília/BR
/
Universidade de São Paulo/BR
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