Genotypes of clinical varicella-zoster virus isolates from Manaus, Brazil
Rev. Soc. Bras. Med. Trop
;
52: e20180166, 2019. tab, graf
Article
Dans Anglais
| LILACS
| ID: biblio-1041564
ABSTRACT
Abstract INTRODUCTION:
Vaccination against varicella-zoster virus (VZV) has been effective and safe in countries that routinely administer the vaccine. Brazil began universal VZV vaccination in 2013. This study aimed to identify VZV genotypes present in Manaus, Brazil prior to widespread immunization.METHODS:
Vesicular lesions or cerebral-spinal-fluid samples were collected from patients diagnosed with VZV, herpes zoster, or meningitis/encephalitis. DNA was extracted, amplified, and sequenced.RESULTS:
Half the isolates were clade-5 viruses and the remaining were divided between the European clades 1 and 3.CONCLUSIONS:
This study provides insights into the circulating VZV genotypes in Manaus prior to widespread vaccination.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Herpèsvirus humain de type 3
/
Infection à virus varicelle-zona
Limites du sujet:
Adolescent
/
Adulte
/
Adulte très âgé
/
Enfant
/
Enfant d'âge préscolaire
/
Femelle
/
Humains
/
Mâle
Pays comme sujet:
Amérique du Sud
/
Brésil
langue:
Anglais
Texte intégral:
Rev. Soc. Bras. Med. Trop
Thème du journal:
Médecine tropicale
Année:
2019
Type:
Article
Pays d'affiliation:
Brésil
/
États-Unis d'Amérique
Institution/Pays d'affiliation:
Centers for Disease Control and Prevention/US
/
Fundação de Medicina Tropical Dr. Heitor Vieira Dourado/BR
/
Hospital Universitário Getúlio Vargas/BR
/
Universidade do Estado do Amazonas/BR
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