Correlation of Low CD4+ Counts with High Dental Caries Prevalence in Children Living with Perinatal HIV/AIDS Undergoing Antiretroviral Therapy
Pesqui. bras. odontopediatria clín. integr
; 19: e4819, 2019. graf
Article
de En
| LILACS, BBO
| ID: biblio-1056838
Bibliothèque responsable:
BR1264.1
ABSTRACT
Abstract Objective:
To investigate the correlation Cluster of Differentiation 4+ (CD4+) counts with a high prevalence of dental caries in Children Living with Perinatal Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (CLWPHA). Material andMethods:
An analytical observational research with a cross-sectional design was conducted at Tertiary General Hospital, Surabaya, Indonesia. Randomized total sampling consisted of 29 CLWPHA 1-12 years old at outpatient ward Infectious Disease Intermediate Unit (UPIPI) Tertiary General Hospital Doctor Soetomo Surabaya. Demographic details and recent CD4+ counts obtained from medical records. Decayed, missing, filled teeth (dmft) in primary teeth and DMFT in permanent teeth index were used. Pearson's and Spearman's Correlation test (p<0.05) were performedResults:
Dental caries prevalence was 86.2%; meanwhile, the dmft/DMFT index score found were high (8.2 / 6.3). CD4+ count and caries showed significant correlation (r=-0.394, p<0.05). Tooth brushing frequency with caries showed a significant correlation (r=-0.419, p<0.05). Antiretroviral (ARV) therapy and caries showed an insignificant negative correlation (p<0.05)Conclusion:
The high prevalence of dental caries in CLWPHA correlated with low CD4+ counts.Mots clés
Texte intégral:
1
Indice:
LILACS
Sujet Principal:
Enfant
/
Syndrome d'immunodéficience acquise
/
VIH (Virus de l'Immunodéficience Humaine)
/
Numération des lymphocytes CD4
/
Caries dentaires
Type d'étude:
Clinical_trials
/
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limites du sujet:
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Pays comme sujet:
Asia
langue:
En
Texte intégral:
Pesqui. bras. odontopediatria clín. integr
Thème du journal:
ODONTOLOGIA
Année:
2019
Type:
Article