Risk of digital ulcers occurrence in systemic sclerosis: a cross-sectional study
Adv Rheumatol
;
59: 14, 2019. tab
Article
Dans Anglais
| LILACS
| ID: biblio-1088621
ABSTRACT
Abstract Background/objective:
Digital ulcers (DUs) represent a frequent complication of systemic sclerosis (SSc). The aim of this study was to evaluate clinical, serological and capillaroscopy features that are associated with DUs in patients with SSc.Methods:
In this bicentric cross-sectional study, 70 patients with SSc were consecutively selected from March 2016 to April 2017. Demographic and clinical features, including the presence of active DUs, were collected. Videocapillaroscopy was performed in all patients.Results:
Among the 70 patients included (mean age of 46.8 years, mean disease duration of 9.41 years), 14 (20%) had active DUs. Based on multivariate analysis, the presence of anti-Scl-70 antibodies, the HAQ-DI score, and the capillary loss score were independently associated with DUs with odds ratios of 7.96 (95% CI 1.32-47.99), 55.77 (95% CI 1.76-1764.28), and 16.66 (95% CI 2.07-133.81), respectively.Conclusions:
The presence of avascular areas in capillaroscopy, elevation of HAQ-DI score and anti-Scl-70 antibodies were independent factors associated with DUs in patients with SSc.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Sclérodermie systémique
/
Ulcère
Type d'étude:
Etude d'étiologie
/
Étude observationnelle
/
Étude de prévalence
/
Facteurs de risque
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Adv Rheumatol
Thème du journal:
Artrite
/
Reumatologia
Année:
2019
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Universidade Federal de São Paulo/BR
/
Universidade Federal do Mato Grosso do Sul/BR
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