Extracorporeal membrane oxygenation and lung transplantation: initial experience at a single brazilian center
Clinics
;
75: e1698, 2020. tab
Article
Dans Anglais
| LILACS
| ID: biblio-1101087
ABSTRACT
OBJECTIVE:
To report initial experience from the use of extracorporeal membrane oxygenation (ECMO) in patients who received lung transplantation.METHODS:
Retrospective study of a single tertiary center in the Brazilian state of São Paulo, a national reference in lung transplantation, based on the prospective collection of data from electronic medical records. The period analyzed extended from January 2009 (beginning of the program) until December 2018.RESULTS:
A total of 75 lung transplants were performed, with ECMO used in 8 (10.7%) cases. Of the patients, 4 (50%) were female. The mean age was 46.4±14.3 years. The causes of the end-stage lung disease that led to transplantation were pulmonary arterial hypertension in 3 (37.5%) patients, bronchiectasis in 2 (25%) patients, pulmonary fibrosis in 2 (25%) patients, and pulmonary emphysema in 1 (12.5%) patient. In our series, 7 (87.5%) cases were sequential bilateral transplantations. Prioritization was necessary in 4 (50%) patients, and in 1 patient, ECMO was used as a bridge to transplantation. The ECMO route was central in 4 (50%), peripheral venovenous in 2 (25%) and peripheral venoarterial in 2 (25%) patients. The mean length of the intensive care unit (ICU) stay was 14±7.5 days and of the hospital stay was 34.1±34.2 days. The mean ECMO duration was 9.3±6.6 days with a 50% decannulation rate. Three patients were discharged (37.5%).CONCLUSION:
Lung transplantation requires complex treatment, and ECMO has allowed extending the indications for transplantation and provided adjuvant support in the clinical management of these patients.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Oxygénation extracorporelle sur oxygénateur à membrane
/
Maladies pulmonaires
Type d'étude:
Étude observationnelle
/
Facteurs de risque
Pays comme sujet:
Amérique du Sud
/
Brésil
langue:
Anglais
Texte intégral:
Clinics
Thème du journal:
Médicament
Année:
2020
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Hospital Israelita Albert Einstein/BR
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