Is the newly defined r2cha2ds2-vasc score a predictor for late mortality in patients undergoing transcatheter aortic valve replacement?
Rev. bras. cir. cardiovasc
; 35(2): 145-154, 2020. tab, graf
Article
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| LILACS
| ID: biblio-1101471
Bibliothèque responsable:
BR1.1
ABSTRACT
Abstract Objective:
To assess the performance of the modified R2CHA2DS2-VASc score for predicting mid-to-long-term mortality (> 30 days) in patients undergoing transcatheter aortic valve replacement (TAVR).Methods:
Data of 78 patients who underwent TAVR were retrospectively reviewed. R2CHA2DS2-VASc score was compared with the European System for Cardiac Operative Risk Evaluation II (EuroSCORE II or ES II) and the transcatheter valve therapytranscatheter aortic valve replacement (TVT-TAVR) risk score.Results:
The mean follow-up period was 17.4±9.9 months (maximum 37 months). Early mortality (first 30 days) was observed in 10 (12.8%) patients, whereas mid-to-long-term mortality (> 30 days) was observed in 26 (33.3%) patients. Non-survivors had higher values of R2CHA2DS2-VASc, ES II, and TAVR scores than survivors (P<0.001, P<0.001, and P=0.001, respectively). Analysis of Pearson's correlation revealed that R2CHA2DS2-VASc score was moderately correlated with ES II and TAVR scores (r=0.51, P<0.001; r=0.44, P=0.001, respectively). Pairwise comparisons of R2CHA2DS2-VASc (area under the curve [AUC] 0.870, 95% confidence interval [CI] 0.776-0.964; P<0.001), ES II (AUC 0.801, 95% CI 0.703-0.899; P<0.001), and TAVR scores (AUC 0.730, 95% CI 0.610-852; P=0.002) showed similar accuracy for predicting mortality. R2CHA2DS2-VASc score is an independent predictor of mortality in multivariable Cox regression analysis. A cutoff value of six for R2CHA2DS2-VASc score showed a sensitivity of 74% and a specificity of 89% for predicting mid-to-long-term mortality.Conclusion:
R2CHA2DS2-VASc score, easily calculated from clinical parameters, is associated with prediction of mid-to-longterm mortality in patients undergoing TAVR.Mots clés
Texte intégral:
1
Indice:
LILACS
Sujet Principal:
Sténose aortique
/
Remplacement valvulaire aortique par cathéter
Type d'étude:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limites du sujet:
Aged
/
Aged80
/
Female
/
Humans
/
Male
langue:
En
Texte intégral:
Rev. bras. cir. cardiovasc
Thème du journal:
CARDIOLOGIA
/
CIRURGIA GERAL
Année:
2020
Type:
Article