Temporal dynamics of human mastadenovirus species in cases of respiratory illness in southern Brazil
Braz. j. microbiol
;
50(3): 677-684, July 2019. ilus., tab
Article
Dans Anglais
| LILACS, SES-RS, CONASS, ColecionaSUS
| ID: biblio-1121770
ABSTRACT
Human mastadenovirus (HAdV) genus is related to several diseases, among them upper and lower respiratory tract illness. HAdV species B, C, D, and E are mainly associated with respiratory infections. The goal of this work was to identify the HAdV species associated with respiratory infections in hospitalized patients from southern Brazil. Samples were collected from 1996 to 2004 and 2011 to 2017. During this period, 28,524 samples were collected, and 9983 were positive for respiratory viruses, being 435 for HAdV. From these 435 samples, 57 were selected for characterization of HAdV species. For screening the presence of HAdV, a partial sequence of the DNA polymerase gene (DNApol gene) was amplified by nested PCR. Partial nucleotide sequencing was performed in positive samples, and HAdV (DNApol gene) was detected in 53 samples species B (28;49.1%), C (16;8.0%), D (2; 3.5%), E (5; 8.7%), and untyped (2; 3.5%). Specie D was found only in 2017 and specie E in 2011 and 2012. The age of the patients ranged from < 1 to 81 years old, and 62.3%were male. No relationship between gender orage and identified HAdV species were observed. In addition, in the period of 20132017, 18 samples from patients who died were analyzed 11 were related to species B, 4 to C, and 2 to D and 1 remained untyped. Circulation of HAdV species D and Evaried over the years, but species B and C were present throughout the evaluated period. In addition, respiratory infections by HAdVaffect elderly and children mainly. (AU)
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Appareil respiratoire
/
Infections de l'appareil respiratoire
/
Mastadenovirus
Limites du sujet:
Adulte très âgé
/
Aged80
/
Enfant
/
Femelle
/
Humains
/
Mâle
Pays comme sujet:
Amérique du Sud
/
Brésil
langue:
Anglais
Texte intégral:
Braz. j. microbiol
Année:
2019
Type:
Article
Institution/Pays d'affiliation:
Rio Grande do Sul (Estado)/BR
/
Rio Grande do Sul (Estado). Secretaria de Estado da saúde/BR
/
Universidade Feevale/BR
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