Association between dietary patterns and renal function in a cross-sectional study using baseline data from the ELSA-Brasil cohort
Braz. j. med. biol. res
;
53(12): e10230, 2020. tab, graf
Article
Dans Anglais
| LILACS, ColecionaSUS
| ID: biblio-1132502
ABSTRACT
Previous analyses of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) identified four main dietary patterns (DP). The aim of this study was to explore the association between the previously defined DP and renal function (RF). A cross-sectional study using the ELSA-Brasil baseline data was carried out. DP ("traditional", "fruits and vegetables", "bakery", and "low sugar/low fat), metabolic syndrome (MS) using the Joint Interim Statement criteria, microalbuminuria (MA), and glomerular filtration rate (eGFR) through the CKD-EPI equation were evaluated. Abnormal RF was defined as eGFR<60 mL·min-1·(1.73 m2)-1 and MA≥3.0 mg/dL. Factors associated with RF were determined and mediation analysis was performed to investigate the association between DP, MS, and RF. A total of 15,105 participants were recruited, with a mean age of 52±9 years; 8,134 participants (54%) were females. The mediation analysis identified indirect associations between "bakery" and "fruits and vegetables", and both were associated with decreased eGFR and albuminuria in both genders, compared with "traditional" and "low sugar/low fat" patterns in the general population. There was a direct association of the "bakery" pattern with MA in men (OR 1.17, 95%CI 1.92-1.48). The "fruits and vegetables" pattern also showed a direct association with reduced eGFR in women (OR 1.65, 95%CI 1.28-2.12), although there was no significance after adjustment. The "fruits and vegetables" and "bakery" DPs were associated with renal dysfunction. The only independent, direct association was between "bakery" DP and MA in men, raising concerns about DP and renal damage in men.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Régime alimentaire
Type d'étude:
Etude d'étiologie
/
Étude observationnelle
/
Étude de prévalence
/
Étude pronostique
/
Facteurs de risque
Limites du sujet:
Adulte
/
Femelle
/
Humains
/
Mâle
Pays comme sujet:
Amérique du Sud
/
Brésil
langue:
Anglais
Texte intégral:
Braz. j. med. biol. res
Année:
2020
Type:
Article
Institution/Pays d'affiliation:
Fundação Oswaldo Cruz/BR
/
Universidade Federal da Bahia/BR
/
Universidade Federal de Minas Gerais/BR
/
Universidade Federal do Ceará/BR
/
Universidade Federal do Espírito Santo/BR
/
Universidade Federal do Rio Grande do Sul/BR
/
Universidade de Fortaleza/BR
/
Universidade de São Paulo/BR
/
University of Southampton/GB
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