Prevalence of red blood cell alloimmunization in multiply transfused patients
Clin. biomed. res
;
40(2): 91-95, 2020.
Article
Dans Anglais
| LILACS
| ID: biblio-1148106
ABSTRACT
Introduction:
To analyze the prevalence of alloantibodies in multiply transfused patients.Methods:
This study was a retrospective, exploratory and descriptive study with a quantitative approach. The study sample comprised 185 patients transfused at a referral service in the city of Passo Fundo, Rio Grande do Sul, from January 2016 to February 2018.Results:
Overall, the antibodies identified were as follows anti-E in 47 patients (18%), anti-D and anti-K in 28 patients each (11%), anti-C in 21 patients (8.1%), and inconclusive antibody results in 23 patients (8.9%). Females were a majority (55.7%), mean age was 48.8 years and mean quantity of blood transfused was 7.2 bags. Cardiovascular disorders were the most common comorbidities, in 39 patients (21.2%), followed by oncological disorders, in 38 patients (18.4%).Conclusion:
Alloimmunization is an important and frequent clinical condition that increases the risk of hemolytic reactions and is associated with significant patient morbidity and mortality. (AU)
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Receveurs de transplantation
/
Anticorps
Type d'étude:
Étude de prévalence
/
Facteurs de risque
Limites du sujet:
Femelle
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Clin. biomed. res
Thème du journal:
Médicament
Année:
2020
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Hospital São Vicente de Paulo/BR
/
Universidade de Passo Fundo/BR
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