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Congenital thymoma
Chand, Momal Tara; Edens, Jacob; Lin, Tayson Taixin; Goshorn, David; Pham, Truc.
  • Chand, Momal Tara; Ascension St John Hospital. Department of Pathology. Detroit. US
  • Edens, Jacob; Ascension St John Hospital. Department of Pathology. Detroit. US
  • Lin, Tayson Taixin; Ascension St John Hospital. Department of Pathology. Detroit. US
  • Goshorn, David; Sacred Heart Childrens Hospital. Spokane. US
  • Pham, Truc; Sacred Heart Childrens Hospital. Spokane. US
Autops. Case Rep ; 11: e2021327, 2021. graf
Article Dans Anglais | LILACS | ID: biblio-1339246
ABSTRACT
Thymomas are a heterogeneous group of tumors arising from the epithelium of the thymus. They are categorized by the proportion of neoplastic epithelia to lymphocytes and by the degree of cytologic atypia. Thymomas constitute 0.2-1.5% of all malignancies and nearly all occur in patients over 20 years. We reviewed the available literature and found less than 50 cases of thymoma reported in children (<18 years of age), the youngest being 4 years old, and no cases in newborns. They represent less than 1% of all mediastinal tumors in children. Due to the limited number of cases in the pediatric population, the diagnosis and treatment in this population is extremely challenging. Thymomas in all age groups may be associated with paraneoplastic syndromes, being myasthenia gravis the most common, which is associated with a worse prognosis in the pediatric population. We present the first case of a newborn infant with congenital thymoma. This case demonstrates a rare tumor in an unusual age group and emphasizes the importance of multidisciplinary teamwork in the decision-making and management of this condition.
Sujets)


Texte intégral: Disponible Indice: LILAS (Amériques) Sujet Principal: Thymome / Tumeurs du thymus Type d'étude: Étude pronostique Limites du sujet: Humains / Mâle / Nouveau-né langue: Anglais Texte intégral: Autops. Case Rep Thème du journal: Anatomia / Patologia Cl¡nica / Patologia Legal Année: 2021 Type: Article Pays d'affiliation: États-Unis d'Amérique Institution/Pays d'affiliation: Ascension St John Hospital/US / Sacred Heart Childrens Hospital/US

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Texte intégral: Disponible Indice: LILAS (Amériques) Sujet Principal: Thymome / Tumeurs du thymus Type d'étude: Étude pronostique Limites du sujet: Humains / Mâle / Nouveau-né langue: Anglais Texte intégral: Autops. Case Rep Thème du journal: Anatomia / Patologia Cl¡nica / Patologia Legal Année: 2021 Type: Article Pays d'affiliation: États-Unis d'Amérique Institution/Pays d'affiliation: Ascension St John Hospital/US / Sacred Heart Childrens Hospital/US