Successful treatment of diffuse cutaneous leishmaniasis caused by Leishmania amazonensis
An. bras. dermatol
;
96(5): 602-604, Sept.-Oct. 2021. graf
Article
Dans Anglais
| LILACS
| ID: biblio-1345132
ABSTRACT
Abstract Diffuse cutaneous leishmaniasis is a rare universal disease associated with an inadequate host cell immune response, caused by different species infantum, aethiopica, major, mexicana, and others, which presents the challenge of a poor therapeutic response. In Brazil, it is caused by L. amazonensis. A case confirmed by histopathology with an abundance of vacuolated macrophages full of amastigotes and lymphocyte scarcity, identified by RFLP-ITS1PCR and in vitro decrease and exhaustion of the host cell immune response to L. amazonensis antigen, was treated early (3 months after the onset) with Glucantime (2 months) and allopurinol (29 months) with clinical cure, after a follow-up for 30 months after treatment.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Leishmania mexicana
/
Leishmaniose cutanée diffuse
/
Leishmaniose cutanée
/
Antiprotozoaires
Type d'étude:
Étude pronostique
Limites du sujet:
Humains
Pays comme sujet:
Amérique du Sud
/
Brésil
langue:
Anglais
Texte intégral:
An. bras. dermatol
Thème du journal:
Dermatologie
Année:
2021
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Universidade de Brasília/BR
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