Carotid doppler ultrasonography in patients with co-existing type 2 diabetes mellitus and hypertension in Nigeria
Ann. Health Res. (Onabanjo Univ. Teach. Hosp.)
;
8(1): 49-62, 2022. figures, tables
Article
Dans Anglais
| AIM
| ID: biblio-1362843
ABSTRACT
Background:
The co-existence of diabetes mellitus (DM) and hypertension (HTN) has been rising globally with subclinical atherosclerotic complications. These vascular changes can be detected using carotid ultrasonography.Objectives:
To determine and compare the carotid arterial structural wall changes and blood flow velocities of adults with co-existing DM and HTN with age-and sex-matched non-diabetic, non-hypertensive controls.Methods:
A cross-sectional comparative study of 300 participants comprising 200 adults with co-existing DM and HTN and 100 age-and sex-matched controls was done. Their carotid arteries were examined bilaterally for plaques, carotid intima media thickness (CIMT) and flow velocities peak systolic velocity (PSV), end diastolic velocity (EDV), pulsatility index (PI) and resistive index (RI) using 412MHz linear array transducer. Visceral obesity and serum lipids were also assessed.Results:
The mean age of the subjects was 56.13 ± 6.93 years; they comprised 38% males and 62% females. The subjects' CIMT was statistically significantly higher (p = 0.001) with a three-fold mean increase (45.5%) compared to the controls (13.7%). Lower flow velocities but higher indices were also observed in the subjects. Strong and significant correlations were observed between EDV and PI r =-0.663, p=>0.001), EDV and RI (r = -0.661, p=>0.001) and PI and RI (r =0.988, p= >0.001)among the subjects.Conclusion:
Significant reduction in flow velocities with increased CIMT may be an early indication of subclinical atherosclerosis. Therefore, carotid ultrasonography should be mandatory in individuals at risk for early detection and possible prevention of atherosclerotic complications.
Texte intégral:
Disponible
Indice:
AIM (Afrique)
Sujet Principal:
Vitesse du flux sanguin
/
Artériopathies carotidiennes
/
Échographie-doppler
/
Diabète de type 2
/
Hypertension artérielle
Type d'étude:
Étude de dépistage
Limites du sujet:
Femelle
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Ann. Health Res. (Onabanjo Univ. Teach. Hosp.)
Année:
2022
Type:
Article
Institution/Pays d'affiliation:
Department of Chemical Pathology, Olabisi Onabanjo University Teaching Hospital/NG
/
Department of Internal Medicine, Endocrine, Olabisi Onabanjo University Teaching Hospital/NG
/
Department of Paediatrics, Endocrine Unit, Babcock University Teaching Hospital/NG
/
Department of Radiology, Lagos State University Teaching Hospital/NG
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Department of Radiology, Olabisi Onabanjo University Teaching Hospital/NG
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