Analysis of potential drug interactions in medical clinic sector in a Hospital of João Pessoa - PB
Braz. J. Pharm. Sci. (Online)
;
58: e18943, 2022. graf
Article
Dans Anglais
| LILACS
| ID: biblio-1364427
ABSTRACT
Abstract The objective of this study was to evaluate drug interactions based on medical records of patients hospitalized in University Hospital Lauro Wanderley (UHLW) in João Pessoa-PB, Brazil. This was a quantitative, descriptive study with a cross-sectional design. This research was conducted in the medical clinic of the above hospital by analyzing pharmaceutical intervention in medical records. The investigated samples consisted of all medical profiles with drug interaction information of patients hospitalized from June 2016 to June 2017. Most of these drug interactions were determined and classified by Micromedex® Solutions database. This research was approved by the Ethics Committee in Institutional Human Research, protocol number 2.460.206. In total, 331 drug interactions were found in 131 medical profiles. Dipyrone, enoxaparin, sertraline, ondansetron, quetiapine, tramadol, bromopride, amitriptyline, and simvastatin were medications that showed highest interactions. According to Anatomical Therapy Classification (ATC), drugs that act on the central nervous system result in more interactions. The most prevalent interaction was between dipyrone and enoxaparin. Some limitations of this study are the lack of notifications and data on drug interactions.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Recherche
/
Dossiers médicaux
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Interactions médicamenteuses
/
Études d'évaluation comme sujet
/
Patients hospitalisés
Type d'étude:
Etude diagnostique
/
Études d'évaluation
/
Guide de pratique
Limites du sujet:
Femelle
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Braz. J. Pharm. Sci. (Online)
Thème du journal:
Farmacologia
/
Teraputica
/
Toxicologia
Année:
2022
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Federal University of Paraiba/BR
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