Relation between red blood cell distribution width and acute kidney injury in patients with sepsis
Einstein (Säo Paulo)
;
20: eAO6828, 2022. tab, graf
Article
Dans Anglais
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LILACS-Express
| LILACS
| ID: biblio-1375334
ABSTRACT
ABSTRACT Objective The objective of the present study is to evaluate the association of red blood cell distribution width with acute kidney injury in sepsis. Methods This is a retrospective study of 849 critically ill patients with sepsis in intensive care unit. Demographic data, renal function, inflammation, complete blood count, and acid-base parameters were compared between acute kidney injury and non-acute kidney injury groups. Therefore, a multivariate analysis was performed to observe independent predictive factors. Results Comparatively, higher levels of C-reactive protein, lactate, red blood cell distribution width, and Simplified Acute Physiology Score 3 were found in the acute kidney injury group. The study showed a higher frequency of women, hemoglobin (Hgb) concentration, platelets, bicarbonate and PaO2/FiO2 ratio in the non-acute kidney injury group. In addition, there was an independent association of comorbidity-chronic kidney disease [OR 3.549, 95%CI 1.627-7.743; p<0.001], urea [OR 1.047, 95%CI 1.036-1.058; p<0.001] and RDW [OR 1.158, 95%CI 1.045-1.283; p=0.005] with acute kidney injury in sepsis patients. Conclusion As an elective risk factor, red blood cell distribution width was independently associated with sepsis-related acute kidney injury. Thus, red blood cell distribution width acts like a predictive factor for sepsis-induced acute kidney injury in intensive care unit admission.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Type d'étude:
Étude observationnelle
/
Étude pronostique
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Facteurs de risque
langue:
Anglais
Texte intégral:
Einstein (Säo Paulo)
Thème du journal:
Médicament
Année:
2022
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Faculdade Israelita de Ciências da Saúde Albert Einstein/BR
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Hospital Israelita Albert Einstein/BR
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Universidade Federal de São Paulo/BR
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