Granulomatous interstitial nephritis secondary to the use of the anti-TNF adalimumab / Nefritis intersticial granulomatosa secundario al uso del anti TNF adalimumab

ABSTRACT

Abstract We present the case of a 56-year-old patient with progressive kidney function deterioration whose kidney biopsy reported granulomatous interstitial nephritis. The medical chart was reviewed, and it was noted that the deterioration coincided with the initiation of the medication adalimumab. It was discontinued and steroid plus cytostatic treatment was begun, with improvement. (Acta Med Colomb 2021; 46. DOIhttps//doi.org/10.36104/amc.2021.2050).

RESUMEN

Resumen Se presenta el caso de una paciente de 56 años, quien presenta deterioro progresivo en la función renal, y en quien la biopsia renal reportó nefritis intersticial granulomatosa. Se revisó historia clínica, y se detectó que el deterioro coincidía con el inicio del medicamento adalimumab. Se suspendió, inicio terapia de esteroide más citostático con mejoría. (Acta Med Colomb 2021; 46. DOIhttps//doi.org/10.36104/amc.2021.2050).