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Efficacy of fetal left ventricular modified myocardial performance index in predicting adverse perinatal outcomes in intrahepatic cholestasis of pregnancy
Gök, Koray; Takmaz, Taha; Köse, Osman; Kapudere, Bilge; Tüten, Nevin; Bostancı, Mehmet Sühha; Özden, Selçuk.
  • Gök, Koray; Sakarya University. Faculty of Medicine. Department of Obstetrics and Gynecology. Sakarya. TR
  • Takmaz, Taha; Bezmialem University. Faculty of Medicine. Department of Obstetrics and Gynecology. Istanbul. TR
  • Köse, Osman; Sakarya Research and Training Hospital. Department of Obstetrics and Gynecology. Sakarya. TR
  • Kapudere, Bilge; Sakarya University. Faculty of Medicine. Department of Obstetrics and Gynecology. Sakarya. TR
  • Tüten, Nevin; Kanuni Sultan Süleyman Research and Training Hospital. Department of Obstetrics and Gynecology. Istanbul. TR
  • Bostancı, Mehmet Sühha; Sakarya University. Faculty of Medicine. Department of Obstetrics and Gynecology. Sakarya. TR
  • Özden, Selçuk; Sakarya University. Faculty of Medicine. Department of Obstetrics and Gynecology. Sakarya. TR
Rev. Assoc. Med. Bras. (1992, Impr.) ; 68(7): 917-921, July 2022. tab, graf
Article Dans Anglais | LILACS-Express | LILACS | ID: biblio-1394600
ABSTRACT
SUMMARY

OBJECTIVE:

This study aimed to evaluate the effectiveness of fetal left ventricular modified myocardial performance index in predicting adverse perinatal outcomes for intrahepatic cholestasis of pregnancy.

METHODS:

A cross-sectional study was conducted, including 51 women with intrahepatic cholestasis of pregnancy and 80 healthy controls. Using Doppler ultrasonography, E-wave, A-wave, isovolumetric contraction time, isovolumetric relaxation time, and ejection time were recorded and the left ventricular modified myocardial performance index was measured.

RESULTS:

Findings showed that the mean left ventricular modified myocardial performance index, isovolumetric contraction time, and isovolumetric relaxation time values were statistically significantly higher while the ejection time and E/A ratios were statistically significantly lower in the intrahepatic cholestasis of pregnancy group than the control group. In the intrahepatic cholestasis of pregnancy group, a statistically significant positive correlation was found between left ventricular modified myocardial performance index and adverse perinatal outcomes in the intrahepatic cholestasis of pregnancy group (r=0.478, p<0.001), while a statistically significant negative correlation was found between the E/A ratio and adverse perinatal outcomes (r=-0.701, p<0.001).

CONCLUSIONS:

For intrahepatic cholestasis of pregnancy cases, high fetal left ventricular modified myocardial performance index values were an indicator of ventricular dysfunction, and this correlated with negative perinatal outcomes.


Texte intégral: Disponible Indice: LILAS (Amériques) Type d'étude: Étude observationnelle / Étude pronostique / Facteurs de risque langue: Anglais Texte intégral: Rev. Assoc. Med. Bras. (1992, Impr.) Thème du journal: Educa‡Æo em Sa£de / GestÆo do Conhecimento para a Pesquisa em Sa£de / Médicament Année: 2022 Type: Article Pays d'affiliation: Turquie Institution/Pays d'affiliation: Bezmialem University/TR / Kanuni Sultan Süleyman Research and Training Hospital/TR / Sakarya Research and Training Hospital/TR / Sakarya University/TR

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Texte intégral: Disponible Indice: LILAS (Amériques) Type d'étude: Étude observationnelle / Étude pronostique / Facteurs de risque langue: Anglais Texte intégral: Rev. Assoc. Med. Bras. (1992, Impr.) Thème du journal: Educa‡Æo em Sa£de / GestÆo do Conhecimento para a Pesquisa em Sa£de / Médicament Année: 2022 Type: Article Pays d'affiliation: Turquie Institution/Pays d'affiliation: Bezmialem University/TR / Kanuni Sultan Süleyman Research and Training Hospital/TR / Sakarya Research and Training Hospital/TR / Sakarya University/TR