Association between Volatile Sulfur Compounds Prevotella intermedia and Matrix Metalloproteinase-8 Expression
Pesqui. bras. odontopediatria clín. integr
;
22: e210002, 2022. tab
Article
Dans Anglais
| LILACS, BBO
| ID: biblio-1422260
ABSTRACT
Abstract Objective:
To determine the correlation between levels of methyl mercaptan (CH3SH) hydrogen sulfide (H2S), the proportion of Prevotella intermedia (Pi), and matrix metalloproteinase-8 (MMP-8) gene expression levels in periodontitis patients accompanied by halitosis. Material andMethods:
Samples were obtained from gingival crevicular fluid (GCF) in the deepest pocket and by swabbing in the tongue coating area in patients with periodontitis presenting with halitosis (n = 23) and healthy subjects as controls (n = 7). The values of CH3SH and H2S were obtained using Oral Chroma. The proportion of Pi and MMP-8 expression levels were evaluated using PCR-RT. All the result was statistically analyzed using SPSS software.Results:
The levels of CH3SH and H2S in participants with PD ≥ 6 mm showed a robust negative correlation with the proportion of P. intermedia in GCF and tongue coating. No statistically significant association was detected between CH3SH and H2S levels and MMP-8 expression levels (p>0.05).Conclusion:
There is no association between CH3SH and H2S levels, the proportion of P. intermedia, and MMP-8 expression in patients with periodontitis accompanied by halitosis (AU).
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Parodontite
/
Prevotella intermedia
/
Matrix metalloproteinase 8
/
Halitose
/
Sulfure d'hydrogène
Type d'étude:
Étude observationnelle
/
Étude de prévalence
/
Facteurs de risque
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Pesqui. bras. odontopediatria clín. integr
Thème du journal:
Dentisterie
Année:
2022
Type:
Article
Pays d'affiliation:
Indonésie
Institution/Pays d'affiliation:
Universitas Indonesia/ID
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