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Tolerance and Adherence of Patients with Chronic Chagas Disease Treated with Benznidazole
Vázquez, Cristina; García-Vázquez, Elisa; Carrilero, Bartolomé; Simón, Marina; Franco, Fuensanta; Iborra, María Asunción; Gil-Gallardo, Luis Javier; Segovia, Manuel.
Affiliation
  • Vázquez, Cristina; Hospital Clínico Universitario Virgen de la Arrixaca. Microbiology Service. El Palmar. ES
  • García-Vázquez, Elisa; Hospital Clínico Universitario Virgen de la Arrixaca. Microbiology Service. El Palmar. ES
  • Carrilero, Bartolomé; Hospital Clínico Universitario Virgen de la Arrixaca. Microbiology Service. El Palmar. ES
  • Simón, Marina; Hospital Clínico Universitario Virgen de la Arrixaca. Microbiology Service. El Palmar. ES
  • Franco, Fuensanta; Hospital Clínico Universitario Virgen de la Arrixaca. Microbiology Service. El Palmar. ES
  • Iborra, María Asunción; Hospital Clínico Universitario Virgen de la Arrixaca. Microbiology Service. El Palmar. ES
  • Gil-Gallardo, Luis Javier; Hospital Clínico Universitario Virgen de la Arrixaca. Microbiology Service. El Palmar. ES
  • Segovia, Manuel; Hospital Clínico Universitario Virgen de la Arrixaca. Microbiology Service. El Palmar. ES
Rev. Soc. Bras. Med. Trop ; Rev. Soc. Bras. Med. Trop;56: e0384, 2023. tab, graf
Article de En | LILACS-Express | LILACS | ID: biblio-1422869
Bibliothèque responsable: BR1.1
ABSTRACT
ABSTRACT

Background:

Chagas disease (CD) treatment is commonly associated with a high incidence of adverse effects. It is crucial to study and update these adverse effects to improve the existing knowledge of which drugs to use and to clarify the information presented to patients.

Methods:

We analyzed the adverse effects of benznidazole in two cohorts of patients a large retrospective study and a small prospective study.

Results:

This large retrospective study described the most and least common adverse effects in our area and characterized our Chagas disease population. This prospective study, along with a close follow-up of the treatment, detected more adverse effects and enhanced the patients' perception of the disease and treatment.

Conclusions:

This information is important for preventing non-medical-related withdrawals and for removing baseless fears. Better knowledge of patients could help us provide better care.
Mots clés

Texte intégral: 1 Indice: LILACS Type d'étude: Observational_studies / Risk_factors_studies langue: En Texte intégral: Rev. Soc. Bras. Med. Trop Thème du journal: MEDICINA TROPICAL Année: 2023 Type: Article

Texte intégral: 1 Indice: LILACS Type d'étude: Observational_studies / Risk_factors_studies langue: En Texte intégral: Rev. Soc. Bras. Med. Trop Thème du journal: MEDICINA TROPICAL Année: 2023 Type: Article