Compounded drugs as an alternative to the therapeutical gaps of inborn errors of metabolism
Braz. J. Pharm. Sci. (Online)
;
59: e21109, 2023. tab, graf
Article
Dans Anglais
| LILACS
| ID: biblio-1429952
ABSTRACT
Abstract Inborn errors of metabolism are rare disorders with few therapeutic options for their treatments, which can make patients suffer with complications. Therefore, compounded drugs might be a promising option given that they have the ability of meeting the patient's specific needs, (i) identification of the main drugs described in the literature; (ii) proposal of compounding systems and (iii) calculation of the budgetary addition for the inclusion of these drugs into the Brazilian Unified Health System. The research conducted a literature review and used management data as well as data obtained from official Federal District government websites. The study identified 31 drugs for the treatment of inborn errors of metabolism. Fifty eight percent (58%) (18) of the medicines had their current demand identified, which are currently unmet by the local Health System. The estimated budget for the production of compounded drugs was of R$363,16.98 per year for approximately 300 patients. This estimated cost represents a budgetary addition of only 0.17% from the total of expenditures planned for drug acquirement. There is a therapeutic gap for inborn errors of metabolism and compounding pharmacies show potential in ensuring access to medicine therapy with a low-cost investment.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Préparations pharmaceutiques
/
Métabolisme
/
Erreurs innées du métabolisme
Type d'étude:
Évaluation en économique de la santé
langue:
Anglais
Texte intégral:
Braz. J. Pharm. Sci. (Online)
Thème du journal:
Farmacologia
/
Teraputica
/
Toxicologia
Année:
2023
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
State Department of Health of the Federal District/BR
/
University of Brasilia/BR
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