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Treatment of acromegaly patients at the Federal University of Triângulo Mineiro (UFTM): Experience Report
de Fátima Borges, Maria; Lara, Beatriz Hallal Jorge; Tomé, Janaíne Machado; de Araújo, Leopoldo Prezia; Bugiga, Flávio Cesar Lucas; Sousa, Júlio Cláudio; Soares, Jacqueline Mendes Fonseca; Dezena, Roberto Alexandre; Ferreira, Beatriz Pires.
  • de Fátima Borges, Maria; Universidade Federal do Triângulo Mineiro. Divisão de Endocrinologia e Metabolismo. Uberaba. BR
  • Lara, Beatriz Hallal Jorge; Universidade Federal do Triângulo Mineiro. Divisão de Endocrinologia e Metabolismo. Uberaba. BR
  • Tomé, Janaíne Machado; Universidade Federal do Triângulo Mineiro. Divisão de Endocrinologia e Metabolismo. Uberaba. BR
  • de Araújo, Leopoldo Prezia; Universidade Federal do Triângulo Mineiro. Divisão de Endocrinologia e Metabolismo. Uberaba. BR
  • Bugiga, Flávio Cesar Lucas; Universidade Federal do Triângulo Mineiro. Divisão de Endocrinologia e Metabolismo. Uberaba. BR
  • Sousa, Júlio Cláudio; Universidade Federal do Triângulo Mineiro. Divisão de Endocrinologia e Metabolismo. Uberaba. BR
  • Soares, Jacqueline Mendes Fonseca; Universidade Federal do Triângulo Mineiro. Divisão de Endocrinologia e Metabolismo. Uberaba. BR
  • Dezena, Roberto Alexandre; Universidade Federal do Triângulo Mineiro. Divisão de Endocrinologia e Metabolismo. Uberaba. BR
  • Ferreira, Beatriz Pires; Universidade Federal do Triângulo Mineiro. Divisão de Endocrinologia e Metabolismo. Uberaba. BR
Clinics ; 72(4): 218-223, Apr. 2017. tab, graf
Article Dans Anglais | LILACS | ID: biblio-840068
ABSTRACT

OBJECTIVE:

To evaluate the effectiveness of the treatment of acromegaly patients at the Federal University of Triangulo Mineiro.

METHODS:

Cross-sectional and retrospective study of thirty cases treated over a period of two decades.

RESULTS:

17 men (56.7%) aged 14-67 years and 13 women aged 14-86 years were analyzed. Twenty-one patients underwent transphenoidal surgery, whichwas associated with somatostatin receptor ligands in 11 patients (39.3%), somatostatin receptor ligands + radiotherapyin 5 patients (17.8%), radiotherapy in 3 patients (10.7%), and radiotherapy + somatostatin receptorligands + cabergoline in 1 patient (3.6%). Additionally, 2 patients underwent radiotherapy and surgeryalone. Six patients received somatostatin receptor ligands before surgery, and 2 were not treated due to refusal and death. Nine patients have died, and 20 are being followed; 13 (65%) have growth hormonelevels o1 ng/mL, and 11 have normal insulin-like growth factor 1 levels.

CONCLUSION:

The current treatment options enable patients seen in regional reference centers to achieve strict control parameters, which allows them to be treated close to their homes.
Sujets)


Texte intégral: Disponible Indice: LILAS (Amériques) Sujet Principal: Acromégalie / Adénomes / Récepteur somatostatine / Adénome hypophysaire à GH Type d'étude: Étude observationnelle / Étude de prévalence / Facteurs de risque Limites du sujet: Adolescent / Adulte / Adulte très âgé / Aged80 / Femelle / Humains / Mâle Pays comme sujet: Amérique du Sud / Brésil langue: Anglais Texte intégral: Clinics Thème du journal: Médicament Année: 2017 Type: Article Pays d'affiliation: Brésil Institution/Pays d'affiliation: Universidade Federal do Triângulo Mineiro/BR

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Texte intégral: Disponible Indice: LILAS (Amériques) Sujet Principal: Acromégalie / Adénomes / Récepteur somatostatine / Adénome hypophysaire à GH Type d'étude: Étude observationnelle / Étude de prévalence / Facteurs de risque Limites du sujet: Adolescent / Adulte / Adulte très âgé / Aged80 / Femelle / Humains / Mâle Pays comme sujet: Amérique du Sud / Brésil langue: Anglais Texte intégral: Clinics Thème du journal: Médicament Année: 2017 Type: Article Pays d'affiliation: Brésil Institution/Pays d'affiliation: Universidade Federal do Triângulo Mineiro/BR