Otoneurological Abnormalities in Patients with Friedreich's Ataxia
Int. arch. otorhinolaryngol. (Impr.)
;
21(1): 79-85, Jan.-Mar. 2017. tab, ilus
Article
Dans Anglais
| LILACS
| ID: biblio-840781
ABSTRACT
Abstract Introduction Friedreich's ataxia is a neurodegenerative disease and progressive by nature. It has autosomal recessive inheritance and early onset inmost cases. Nystagmus and hearing loss (in some cases) make up some of the common symptoms seen in this disorder. Objective The objective of this study is to examine vestibular disorders in patientswith Friedreich ataxia. Methods We conducted a retrospective cross-sectional study. We evaluated 30 patients with ages ranging from six to 72 years (mean age of 38.6 ( 14.7). The patients underwent the following procedures anamnesis, ENT, and vestibular evaluations. Results Clinically, the patients commonly had symptoms of incoordination of movement (66.7%), gait disturbances (56.7%), and dizziness (50%). In vestibular testing, alterations were predominantly evident under caloric testing (73.4%), gaze nystagmus testing (50.1%), rotational chair testing (36.7%), and optokinetic nystagmus testing (33.4%). The presence of alterations occurred under examination in 90% of subjects, with the majority occurring in those with central vestibular dysfunction (70% of the examinations). Conclusion The most evident neurotological symptoms were incoordination of movement, gait disturbances, and dizziness. Alterations in vestibular examinations occurred in 90% of patients, mostly in the caloric test, with a predominance of deficient central vestibular system dysfunction.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Signes et symptômes
/
Ataxie de Friedreich
/
Dégénérescences spinocérébelleuses
Type d'étude:
Etude diagnostique
/
Etude d'étiologie
/
Étude observationnelle
Limites du sujet:
Adolescent
/
Adulte
/
Adulte très âgé
/
Enfant
/
Femelle
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Int. arch. otorhinolaryngol. (Impr.)
Thème du journal:
Otolaryngologie
Année:
2017
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Universidade Tuiuti do Paraná/BR
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