Reparação microcirúrgica de nervo facial de ratos Wistar por meio de sutura: parte 2 / Microsurgical reparation of Wistar rats facial nerve through suture: part 2

RESUMO

O nervo facial direito de 20 ratos da raça Wistar foi seccionado, e as extremidades foram aproximadas por um ponto simples inicial e envolvidas por uma bainha de BioFill. As mudanças histológicas observadas foram proliferação de tecido fibroso, invasão do tecido nervoso por mastócitos e fibroblastos e presença de fibrilas de colágeno. O uso da bainha de BioFill oferece vantagens porque é responsável pelo melhor direcionamento das fibras nervosas

ABSTRACT

The right-side facial nerve of 20 Wistar rats was trans-sectioned and, immediately treated with three plain epineural suture stitches. Analysis of the results was based on histopathological aspects of the anastomotic area. It was noticed that the presence of the suture material was responsible for the poor directioning of the nerve fibers and the neuroma formation in the anastomosis area, due to the collision of the regenerating nerve fibers with the granulomatous reaction to the suture string. Wallerian degeneration and proliferation of fibrous tissue were noticed