Study of factors affecting the incidence of skin cancer in patients after liver transplant
An. bras. dermatol
;
92(4): 492-498, July-Aug. 2017. tab, graf
Article
Dans Anglais
| LILACS
| ID: biblio-886986
ABSTRACT
Abstract Background:
Many factors are currently being identified as potential inductors of skin cancer in patients after a liver transplant, among them, immunosuppressive regimen.Objective:
To study the factors that influence the incidence of skin cancer in patients after liver transplant.Methods:
We have carried out a retrospective and observational study with 170 transplanted patients who had undergone transplantation from 1997 to 2010. We have adjusted the multiple logistic regression model (saturated model) to the ensemble of collected data using skin cancer as dependent variable, indicated in anatomopathological analysis between 1997 and 2014.Results:
Incidence of skin cancer was 9.4%. Predictors were incidence of diabetes in the third year after the transplantation (p=0.047), not using tacrolimus in the first year after the transplantation (p=0.025) and actinic keratosis (p=0.003). StudyLimitations:
An important limitation is that the interpretation of the results was based on information collected of patients undergoing transplantation at a single center. Future research, multicentric and involving larger and more diverse populations, are needed.Conclusions:
Factors found might contribute to Brazilian surveillance programs associated with decreased incidence of skin cancer.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Tumeurs cutanées
/
Carcinome basocellulaire
/
Carcinome épidermoïde
/
Immunosuppression thérapeutique
/
Transplantation hépatique
Type d'étude:
Etude d'étiologie
/
Etude d'incidence
/
Étude observationnelle
/
Étude pronostique
/
Facteurs de risque
Limites du sujet:
Adulte
/
Femelle
/
Humains
/
Mâle
Pays comme sujet:
Amérique du Sud
/
Brésil
langue:
Anglais
Texte intégral:
An. bras. dermatol
Thème du journal:
Dermatologie
Année:
2017
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Universidade Estadual de Campinas/BR
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS