Thickness of carotid intima and epicardial fat in rosacea: a cross-sectional study
An. bras. dermatol
;
92(6): 820-825, Nov.-Dec. 2017. tab
Article
Dans Anglais
| LILACS
| ID: biblio-887113
ABSTRACT
Abstract Background:
Rosacea is a chronic facial skin disease associated with excessive inflammatory response to various triggers. Although some studies have supported the increased risk of cardiovascular diseases in rosacea, it has not been completely accepted.Objective:
We aimed to investigate epicardial fat thickness and carotid intima-media thickness as cardiovascular risk predictors in rosacea patients.Methods:
We conducted a cross-sectional study including 40 rosacea patients and 40 controls. Demographic data, epicardial fat thickness, carotid intima-media thickness, lipid parameters, biochemical parameters, presence of insulin resistance, and presence of metabolic syndrome of the participants were recorded.Results:
Forty rosacea patients (31 female and 9 male) and 40 controls (30 female and 10 male) were enrolled in the study. Rosacea patients had significantly higher epicardial fat thickness and carotid intima-media thickness volumes than controls (P<0.001). In the multivariate logistic regression analysis, epicardial fat thickness was independently related to presence of rosacea (P<0.001, OR=13.31). In the multiple linear regression analysis, the epicardial fat thickness was independently associated with rosacea (β= 0.47, P<0.001), carotid intima-media thickness (β= 0.36, P<0.001), and systolic blood pressure (β=0.19, P=0.015) and the carotid intima-media thickness was independently associated with epicardial fat thickness (β= 0.6, P<0.001). The epicardial fat thickness levels were correlated with carotid intima-media thickness (r=0.63, P<0.001), LDL (r=0.23, P=0.037), systolic blood pressure (r=0.45, P<0.001), and diastolic blood pressure levels (r=0.37, P=0.001). The carotid intima-media thickness levels were correlated with epicardial fat thickness (r=0.63, P<0.001), systolic blood pressure (r=0.04, P<0.001), and diastolic blood pressure levels (r=0.27, P=0.016). Studylimitations:
The small number of participants.Conclusions:
Examination and follow-up of rosacea patients for cardiovascular diseases may be recommended practices.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Péricarde
/
Maladies cardiovasculaires
/
Tissu adipeux
/
Rosacée
/
Épaisseur intima-média carotidienne
Type d'étude:
Etude d'étiologie
/
Étude observationnelle
/
Étude de prévalence
/
Étude pronostique
/
Facteurs de risque
Limites du sujet:
Adulte
/
Femelle
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
An. bras. dermatol
Thème du journal:
Dermatologie
Année:
2017
Type:
Article
Pays d'affiliation:
Turquie
Institution/Pays d'affiliation:
Mugla Sitki Kocman University/TR
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