Evaluation of cross reactivity between Trypanosoma cruzi and Leishmania infantum in serologically ineligible blood donors due to chagas diseas
Rev. patol. trop
;
46(1): 113-119, abr. 2017. tab
Article
Dans Anglais
| LILACS
| ID: biblio-913450
ABSTRACT
Inconclusive serological screening for Trypanosoma cruzi has been a problem for blood banks. This study examined the performance of serological techniques for Chagas disease in reagent samples from blood bank screenings and verified the possibilities of cross reactivity with visceral leishmaniasis. 68 samples of reagent donors tested with ELISA for Chagas disease were evaluated by other techniques and for the detection of anti-Leishmania antibodies. Four donors (5.9%) with positive results for T. cruzi were positive for ELISA Kalazar Detect (visceral leishmaniasis),three of which were confirmed by Western blot. This study confirms the specificity of the tests for Chagas disease in blood banks and reinforces the urgent adoption of measures to assess the real risk of transfusion transmission of visceral leishmaniasis
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Maladie de Chagas
langue:
Anglais
Texte intégral:
Rev. patol. trop
Thème du journal:
Médecine tropicale
/
Pathologie
Année:
2017
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Fundação Hemominas/BR
/
Universidade Estadual de Montes Claros/BR
/
Universidade Federal de Lavras/BR
/
Universidade Federal do Triângulo Mineiro/BR
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