What are the advantages of living in a community? A microbial biofilm perspective!
Mem. Inst. Oswaldo Cruz
;
113(9): e180212, 2018. tab, graf
Article
Dans Anglais
| LILACS
| ID: biblio-955119
ABSTRACT
Biofilm formation is the preferred mode of growth lifestyle for many microorganisms, including bacterial and fungal human pathogens. Biofilm is a strong and dynamic structure that confers a broad range of advantages to its members, such as adhesion/cohesion capabilities, mechanical properties, nutritional sources, metabolite exchange platform, cellular communication, protection and resistance to drugs (e.g., antimicrobials, antiseptics, and disinfectants), environmental stresses (e.g., dehydration and ultraviolet light), host immune attacks (e.g., antibodies, complement system, antimicrobial peptides, and phagocytes), and shear forces. Microbial biofilms cause problems in the hospital environment, generating high healthcare costs and prolonged patient stay, which can result in further secondary microbial infections and various health complications. Consequently, both public and private investments must be made to ensure better patient management, as well as to find novel therapeutic strategies to circumvent the resistance and resilience profiles arising from biofilm-associated microbial infections. In this work, we present a general overview of microbial biofilm formation and its relevance within the biomedical context.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Biofilms
/
Phénomènes physiologiques bactériens
/
Champignons
langue:
Anglais
Texte intégral:
Mem. Inst. Oswaldo Cruz
Thème du journal:
Médecine tropicale
/
Parasitologie
Année:
2018
Type:
Article
Pays d'affiliation:
Brésil
/
Iran
Institution/Pays d'affiliation:
Faculdades São José/BR
/
Iran University of Medical Sciences/IR
/
Universidade Federal do Rio de Janeiro/BR
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