Effect of plasma level of vitamin d on postoperative atrial fibrillation in patients undergoing isolated coronary artery bypass grafting
Rev. bras. cir. cardiovasc
;
33(3): 217-223, May-June 2018. tab, graf
Article
Dans Anglais
| LILACS
| ID: biblio-958413
ABSTRACT
Abstract Objective:
Postoperative atrial fibrillation (PoAF) is a common complication after coronary artery bypass grafting (CABG). The aim of the present study was to evaluate the association between development of PoAF and vitamin D levels in patients undergoing isolated CABG.Methods:
This prospective randomized clinical trial was conducted on the patients with isolated CABG. The study was terminated when 50 patients in both PoAF(+) group and PoAF(-) group were reached. Development of AF until discharge period was assessed. Vitamin D level was measured immediately after AF; it was measured on the discharge day for the patients without PoAF. Predictive values of the independent variables were measured for the development of PoAF.Results:
The groups were separated as PoAF(-) group (66% male, mean age 58.18±10.98 years) and PoAF(+) group (74% male, mean age 61.94±10.88 years). 25(OH) vitamin D level (OR=0.855, 95% CI 0.780-0.938, P=0.001) and > 65 years (OR=3.525, 95% CI 1.310-9.483, P=0.013) were identified as an independent predictor of postoperative AF after CABG surgery in multivariate analysis. The cut-off level for 25(OH) vitamin D level in receiver-operating characteristic curve analysis was determined as 7.65 with sensitivity of 60% and specificity of 64% for predicting PoAF (area under the curve 0.679, P=0.002).Conclusion:
Vitamin D level is considered an independent predictor for development of PoAF. Lower vitamin D levels may be one of the reasons for PoAF.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Complications postopératoires
/
Fibrillation auriculaire
/
Vitamine D
/
Pontage aortocoronarien
Type d'étude:
Essai clinique contrôlé
/
Etude d'étiologie
/
Étude observationnelle
/
Étude pronostique
/
Facteurs de risque
Limites du sujet:
Adulte très âgé
/
Femelle
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Rev. bras. cir. cardiovasc
Thème du journal:
Cardiologie
/
Chirurgie générale
Année:
2018
Type:
Article
Pays d'affiliation:
Turquie
Institution/Pays d'affiliation:
University of Health Sciences/TR
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