Potencial of different hydroxyapatites as biomaterials in the bone remodeling
Acta cir. bras
;
33(9): 816-823, Sept. 2018. tab, graf
Article
Dans Anglais
| LILACS
| ID: biblio-973498
ABSTRACT
Abstract Purpose:
To analyze the therapeutic potentials of different hydroxyapatites used for the correction of bone defects in rats.Methods:
Forty rats, male, albino wistar, were distributed in 4 groups. They were submitted to a 3.5 mm defect in tibia. They received low purity hydroxyapatite, Strontium hydroxyapatite and hydroxyapatite doped with gallium, having a seven day evaluation time. Histopathology slides were stained with hematoxylin-eosin, for morphological evaluation. Were analyzed inflammatory processes, necrosis, presence of osteoclasts and osteoblasts, presence of the material, presence of white cells, neovascularization and bone neoformation.Results:
It was observed that the groups HAPSr and HAPGa, presented better results of trabecular bone, hyaline cartilage and bone marrow more organized.Conclusion:
There was improvement in the repair of the bone defect produced, showing that these hydroxyapatites are effective osteoinductive, osteoconductive, osteintegrant agents and have biocompatibility, and may be indicated for use in defect repairs.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Tibia
/
Matériaux biocompatibles
/
Remodelage osseux
/
Substituts osseux
/
Hydroxyapatites
Limites du sujet:
Animaux
langue:
Anglais
Texte intégral:
Acta cir. bras
Thème du journal:
Chirurgie générale
/
Procedimentos Cir£rgicos Operat¢rios
Année:
2018
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
UFMS/BR
/
Universidade Federal do Mato Grosso do Sul/BR
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS