The influenza season 2016/17 in Bucharest, Romania - surveillance data and clinical characteristics of patients with influenza-like illness admitted to a tertiary infectious diseases hospital
Braz. j. infect. dis
;
22(5): 377-386, Sept.-Oct. 2018. tab, graf
Article
Dans Anglais
| LILACS
| ID: biblio-974239
ABSTRACT
ABSTRACT Background:
Influenza continues to drive seasonal morbidity, particularly in settings with low vaccine coverage.Objectives:
To describe the influenza cases and viral circulation among hospitalized patients.Methods:
A prospective study based on active surveillance of inpatients with influenza-like illness from a tertiary hospital in Bucharest, Romania, in the season 2016/17.Results:
A total of 446 patients were tested, with a balanced gender distribution. Overall, 192 (43%) patients tested positive for influenza, with the highest positivity rate in the age groups 3-13 years and >65 years. Peak activity occurred between weeks 1 and 16/2017, with biphasic distribution A viruses were replaced by B viruses from week 9/2017; B viruses predominated (66.1%). Among the 133 (69.3%) subtyped samples, all influenza A were subtype H3 (n = 57) and all influenza B were B/Victoria (n = 76). Patients who tested positive for influenza presented fewer comorbidities (p = 0.012), except for the elderly, in whom influenza was more common in patients with comorbidities (p = 0.050). Disease evolution was generally favorable under antiviral treatment. The length of hospital stay was slightly longer in patients with influenza-like illness who tested patients negative for influenza (p = 0.031).Conclusions:
Distinctive co-circulation of A/H3 and B/Victoria in Bucharest, Romania in the 2016/17 influenza season was found. While the A/H3 subtype was predominant throughout Europe that season, B/Victoria appears to have circulated specifically in Romania and the Eastern European region, predominantly affecting preschoolers and school children.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Saisons
/
Syndrome respiratoire aigu sévère
/
Grippe humaine
/
Surveillance épidémiologique
Type d'étude:
Étude observationnelle
/
Facteurs de risque
/
Étude de dépistage
Limites du sujet:
Adolescent
/
Adulte
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Adulte très âgé
/
Enfant
/
Enfant d'âge préscolaire
/
Femelle
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Humains
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Bébé
/
Mâle
Pays comme sujet:
Europe
langue:
Anglais
Texte intégral:
Braz. j. infect. dis
Thème du journal:
Maladies transmissibles
Année:
2018
Type:
Article
Pays d'affiliation:
Roumanie
Institution/Pays d'affiliation:
Cantacuzino Military-Medical Research-Development National Institute/RO
/
National Institute for Infectious Diseases "Prof. Dr. Matei Balș"/RO
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