What do Cochrane systematic reviews say about the use of cannabinoids in clinical practice?
São Paulo med. j
;
136(5): 472-478, Sept.-Oct. 2018. tab
Article
Dans Anglais
| LILACS
| ID: biblio-979377
ABSTRACT
ABSTRACT BACKGROUND:
The therapeutic effects of cannabinoid compounds have been the center of many investigations. This study provides a synthesis on all Cochrane systematic reviews (SRs) that assessed the use of cannabinoids as a therapeutic approach. DESIGN ANDSETTING:
Review of SRs, conducted in the Discipline of Evidence-Based Medicine, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP).METHODS:
A broad search was conducted in the Cochrane Database of Systematic Reviews to retrieve any Cochrane SRs that assessed the efficacy and safety of cannabinoids as a therapeutic approach. The results and key characteristics of all reviews included were summarized and discussed.RESULTS:
Eight SRs were included. They assessed the use of cannabinoids for the following types of conditions neurological (two SRs), psychiatric (two SRs), rheumatological (one SR), infectious (one SR) and oncological (two SRs). There was moderate-quality evidence showing that the use of cannabinoids reduced nausea and vomiting among adults, compared with placebo. Additionally, there was moderate-quality evidence showing that there was no difference between cannabinoids and prochlorperazine regarding the number of participants who reported vomiting, in this same population.CONCLUSIONS:
This review identified eight Cochrane systematic reviews that provided evidence of unknown to moderate quality regarding the use of cannabinoids as a therapeutic intervention. Further studies are still imperative for solid conclusions to be reached regarding practical recommendations.
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Cannabinoïdes
/
Revues systématiques comme sujet
Type d'étude:
Essai clinique contrôlé
/
Guide de pratique
/
Étude pronostique
/
Revues systématiques évaluées
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
São Paulo med. j
Thème du journal:
Cirurgia Geral
/
Cincia
/
Ginecologia
/
Médicament
/
Medicina Interna
/
Obstetr¡cia
/
Pediatria
/
Sa£de Mental
/
Sa£de P£blica
Année:
2018
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Universidade Federal de São Paulo/BR
/
Universidade Metropolitana de Santos/BR
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