Evolutive study of rheumatic carditis cases treated with corticosteroids in a Public Hospital / Estudo evolutivo de casos de cardite reumática tratados com corticosteróides em um hospital público
Int. j. cardiovasc. sci. (Impr.)
;
31(6): 578-584, nov.- dez. 2018. tab
Article
Dans Anglais
| LILACS
| ID: biblio-979722
ABSTRACT
Background:
Rheumatic carditis is a challenge for treatment and secondary prophylaxis, due to severe valve sequelae.Objective:
To evaluate the cases of rheumatic carditis in patients under 18 years old treated with corticosteroids.Methods:
An observational, longitudinal and retrospective study was carried out on the profile of patients, in the period of 2000-2015. We selected those who received corticosteroid therapy at immunosuppressive doses, for the treatment of carditis and were aged 5 to 18 years. Data were extracted from medical records. Calculations of averages, standard deviations, medians and interquartile ranges, ratios and 95% confidence intervals were obtained. Chi-square and Wilcoxon tests were applied for comparisons. The level of significance was 5%.Results:
Of the 93 cases, 93.53% developed moderate or severe carditis. Mitral regurgitation was detected in 100% of the sample. Pulse therapy was administered in 11.83%. Surgery was performed in 23.69% of patients mitral, aortic and/or tricuspid valve repair or replacement. The evolution of the cases was favorable in 70.96%. There was a good response among those who received only clinical treatment and those who belonged to the surgical group. The comparison of the initial and posterior valve lesions to the corticoid use was statistically significant (p < 0.001). A difference between the ejection fraction medians was observed (p = 0.048). Hospitalization was required twice or more for 45.16% of the patients. The mortality rate was 5.38%.Conclusions:
The patients showed significant clinical improvement. The treatment was effective, reducing trivalvular impairment
Texte intégral:
Disponible
Indice:
LILAS (Amériques)
Sujet Principal:
Rhumatisme articulaire aigu
/
Hormones corticosurrénaliennes
/
Hôpitaux publics
/
Myocardite
Type d'étude:
Étude observationnelle
/
Facteurs de risque
Limites du sujet:
Adolescent
/
Enfant
/
Femelle
/
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Int. j. cardiovasc. sci. (Impr.)
Thème du journal:
Cardiologie
Année:
2018
Type:
Article
Pays d'affiliation:
Brésil
Institution/Pays d'affiliation:
Instituto Estadual de Cardiologia Aloysio de Castro/BR
/
Universidade Federal Fluminense/BR
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