case of Gitelman's syndrome presenting with hypocalcemia

ABSTRACT

Gitelman's syndrome [GS] is an autosomal recessive disorder caused by a defect of the thiazide-sensitive NaCl cotransporter [TSC] at the distal tubule, characterized by hypomagnesemia, hypokalemic alkalosis and hypocalciuria. This condition was previously confused with Bartter's syndrome [BS]. The documentation of hypocalciuria helps to differentiate this syndrome from BS. We report a 35-year-old female patient presented to our hospital with a history of muscle weakness and carpal spasm. She showed hypokalemia, hypocalcemia, hypomagnesemia and hypocalciuria. She was treated with electrolyte supplements