Chelating tendencies of some sulpha drugs
Egyptian Journal of Pharmaceutical Sciences. 1988; 29 (1-4): 457-63
Dans Anglais
| IMEMR
| ID: emr-10369
ABSTRACT
The acid dissociation constant of sulfadiazine, sulfamerazine and sulfasomidine in 50% ethanolic solution were determined by pH-metric titration at temperature 30C and in different ionic strength. Also, their formation constants with Cu[II], Zn[II], Ni[II], Co[II], Mn[II] have been studied. The free energies of the complexes formed were deduced and the relation between the stabilities of these complexes and the ionization potenital of the cautions were discussed
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Indice:
Méditerranée orientale
Sujet Principal:
Sulfamérazine
/
Chélateurs
langue:
Anglais
Texte intégral:
Egypt. J. Pharm. Sci.
Année:
1988
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