Eosinophilic granuloma: a rare presentation of Langerhans cell histiocytosis in a young female
JPAD-Journal of Pakistan Association of Dermatologists. 2007; 17 (3): 190-194
Dans Anglais
| IMEMR
| ID: emr-104655
ABSTRACT
Histiocytosis encompasses a group of diverse disorders that have in common, as a primary event, the accumulation and infiltration of monocytes, maerophages, and dendritic cells in the affected tissues. Langerhans cell histiocytosis [LCH] can be local and asymptomatie, as in isolated bone lesions, or it can involve multiple organs and systems with significant symptomatology and consequences. Thus, the clinical manifestations depend on the site of the lesions and organs and systems involved and theft functions. We report a case of a 35-year-old lady who presented with skin lesions in presternal area mimicking very closely to those of scrofuloderma [a form of skin tuberculosis]. She had been treated with antituberculous therapy thrice with no benefit. There was no evidence of systemic involvement. Diagnosis of LCH was confirmed on histopathological findings of skin lesion and markers. Patient was treated with oral methttrexate with resolution of lesions
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Indice:
Méditerranée orientale
Sujet Principal:
Granulome éosinophile
/
Méthotrexate
Type d'étude:
Enquête cas-témoins / Études cas/témoins
Limites du sujet:
Femelle
/
Humains
langue:
Anglais
Texte intégral:
J. Pak. Assoc. Dermatol.
Année:
2007
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