Primary splenic hodgkin's disease in a patient with chronic granulomatous disease, a case report

ABSTRACT

Here we report a 20-year-old male, a known case of chronic granulomatous disease [CGD], who presented with fever and splenomegaly. After splenectomy, primary splenic Hodgkin's disease was diagnosed. Immunohistochemistry confirmed the diagnosis [positive CD15 and CD30]. With chemotherapy, his fever was subsided and now after 6 months, he is doing well. Although primary immune deficiencies have been reported to show an increased tendency to develop malignancies, until now there has been no report of a patient with CGD and Hodgkin's disease